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Complex Health Conditions

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CHRONIC & COMPLEX HEALTH – A ROOT-CAUSE APPROACH

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At Re:Health, we specialise in supporting people with chronic, complex, and multi-system health conditions, helping to uncover the root causes of persistent symptoms that often go unexplained or overlooked. 

Conditions like autoimmune diseases, mast cell activation syndrome (MCAS), chronic fatigue syndrome (CFS), chronic inflammatory response syndrome (CIRS), chronic infections, and environmental illness can be deeply frustrating, exhausting, and life-altering. Many of our clients have seen multiple practitioners, tried countless treatments, and still feel like they are searching for answers.

We take a whole-body, investigative approach, using advanced lab testing, personalised nutrition, and functional medicine strategies to piece together the puzzle—so you can move toward lasting relief and a better quality of life.

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The Re:Health Approach

BEYOND SYSTEM MANAGEMENT

Complex conditions rarely have a single cause or simple solution. They often stem from immune dysregulation, chronic inflammation, gut imbalances, environmental exposures, or stealth infections that trigger a cascade of dysfunction throughout the body.

Rather than suppressing symptoms, we take a systems-based approach, identifying the underlying imbalances driving chronic illness and creating a targeted, personalised plan to help your body recover and rebalance.

Key Areas We Assess & Support

AUTOIMMUNE CONDITIONS & IMMUNE DYSREGULATION

Autoimmune diseases such as Hashimoto’s, Rheumatoid Arthritis, Lupus, Multiple Sclerosis, Psoriasis, and inflammatory bowel disease (IBD) are often driven by chronic inflammation, gut dysfunction, and immune system overactivation. We assess immune triggers, gut permeability, and inflammatory pathways to help bring balance.

CHRONIC INFLAMMATORY RESPONSE SYNDROME (CIRS) & MOULD ILLNESS

Chronic exposure to mould, biotoxins, and other environmental toxins can lead to persistent inflammation, neurological symptoms, extreme fatigue, brain fog, and immune dysregulation. We take a Shoemaker Protocol-informed approach, assessing genetic susceptibility, immune markers, and detox pathways to support recovery.

MAST CELL ACTIVATION SYNDROME (MCAS) & HISTAMINE INTOLERANCE 

Mast cells play a crucial role in immune defence, but in MCAS, they become overactive—leading to unpredictable reactions, inflammation, hives, flushing, headaches, fatigue, and neurological symptoms. We investigate histamine metabolism, triggers, and stabilisation strategies.

CHRONIC FATIGUE SYNDROME (CFS) & MITOCHONDRIAL DYSFUNCTION

CFS is more than just fatigue—it’s a condition deeply tied to mitochondrial dysfunction, immune dysregulation, viral reactivation, and post-exertional malaise. We explore cellular energy production, oxidative stress, and viral/inflammatory drivers to support recovery.

CHRONIC INFECTIONS & STEALTH PATHOGENS 

Viruses (EBV, CMV, herpesviruses), Lyme disease, co-infections, mycotoxins, and intracellular bacteria can persist for years, driving immune dysfunction, neurological symptoms, and fatigue. We assess immune function, pathogen load, and inflammatory markers to address underlying infections and use micro-immunotherapy to gently restore balance.

TOXICITY, HEAVY METALS & DETOXIFICATION PATHWAYS 

The body’s detox pathways play a crucial role in eliminating toxins, chemicals, and environmental pollutants that may contribute to neuroinflammation, fatigue, and immune dysfunction. We investigate liver function, phase 1 & 2 detoxification, and heavy metal burden.

GUT HEALTH & MICROBIOME IMBALANCES 

The gut is at the centre of immune function, and conditions like leaky gut, dysbiosis, SIBO, and fungal overgrowth can drive autoimmune activation, systemic inflammation, and nutrient malabsorption.

MITOCHONDRIAL HEALTH & ENERGY PRODUCTION 

The cells’ energy factories (mitochondria) are often impaired in CFS, autoimmune conditions, and environmental illness, contributing to fatigue, brain fog, and muscle weakness. We focus on optimising mitochondrial function, oxidative stress defence, and energy metabolism.

HORMONAL IMBALANCES & STRESS RESPONSE 

Chronic illness often disrupts the HPA axis (hypothalamic-pituitary-adrenal system), leading to cortisol imbalances that drive fatigue, brain fog, and immune dysregulation. We assess adrenal function, sex hormones, and thyroid balance.

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How can we help you

CIRS & Mould

Illness

Chronic Inflammatory Response Syndrome (CIRS), often referred to as mould illness, is a complex, multi-system condition triggered by prolonged exposure to biotoxins

Mast Cell Activation

Syndrome

A chronic condition in which mast cells, a type of immune cell, become overactive and release excessive amounts of inflammatory chemicals.

Chronic Fatigue

Syndrome & ME

Known also as Myalgic Encephalomyelitis (ME), is a complex and debilitating condition characterised by profound fatigue that does not improve with rest

Long Covid

Support

Long COVID refers to persistent symptoms that continue for weeks or months after the acute phase of a COVID-19 infection.

Autoimmunity

Multiple Sclerosis (MS) is a chronic autoimmune condition where the immune system attacks the protective covering of nerve fibres

Chronic

Infections

Occur when the body is unable to fully eliminate pathogens, such as bacteria, viruses, or fungi, leading to ongoing immune activation and inflammation

Image by Drew Hays

Advanced Functional Testing for Complex conditions

We use comprehensive lab testing to move beyond guesswork and identify the root causes of chronic and complex conditions. Read more about lab testing here 

YOUR PERSONALISED COMPLEX CONDITION PLAN

Using data-driven insights, we create a targeted, step-by-step plan to support immune regulation, mitochondrial function, detoxification, and systemic balance. This may include:

Precision Nutrition Strategies – A tailored approach to reduce inflammation, stabilise immune function, and optimise detox pathways.

Targeted Nutritional & Botanical Support – Using evidence-based supplements, mitochondrial cofactors, and anti-inflammatory support.

Nervous System & Stress Resilience – Supporting vagus nerve function, nervous system regulation, and trauma-informed approaches to healing.

Ongoing Monitoring & Refinements – Regular check-ins to track progress and adjust your personalised plan.

A Science-Backed Approach to Complex, Chronic Illness

If you’ve been living with persistent symptoms, unexplained fatigue, immune dysfunction, or environmental illness, our Functional Medicine approach provides a clear roadmap toward healing—even when other approaches have fallen short.

 

Uncover the hidden triggers and biochemical imbalances driving your symptoms

Support immune regulation, detoxification, and cellular energy production

​Address root causes, not just manage symptoms—so you can regain control of your health

Frequently asked questions

  • How does nutrition impact mental health?
    Mental health is deeply connected to brain chemistry, gut health, and nutrient balance. We assess key neurotransmitters, blood sugar regulation, inflammation, and nutritional deficiencies to support stable mood and emotional well-being.
  • How long does it take to see results?
    Some clients notice improvements in weeks, while deeper imbalances may take 3–6 months to fully address. Our approach provides a step-by-step roadmap, supporting gradual and sustainable progress.
  • Can you help with treatment-resistant depression or anxiety?
    Yes, we specialise in complex mental health cases, often working with clients who haven’t found success with conventional treatments. We dig deeper into underlying factors like gut health, methylation, histamine issues, and inflammation to create a personalised strategy.
  • Do you replace medications, or can I work with you alongside my current treatment?
    We work alongside your existing treatment plan, complementing any medications with targeted nutrition and lifestyle strategies. Our approach is root-cause-focused, aiming to improve long-term resilience and reduce dependency on medications where appropriate.
  • What kind of testing do you do for mental health concerns?
    We offer genetic testing, organic acids testing, blood nutrient panels, and hormone assessments to look at neurotransmitter imbalances, methylation, inflammation, gut health, and nutrient status—all key factors in mental well-being.
  • Do you support children or teens with mental health challenges?
    Yes - absolutely. Yes, we provide comprehensive support for teenagers and children experiencing anxiety, depression, OCD, mood imbalances, and behavioural challenges. Our approach looks beyond symptoms to uncover underlying imbalances in brain chemistry, gut health, nutrient status, and hormone regulation. We recognise that mental health challenges in young people can be complex and often involve factors such as stress, diet, blood sugar imbalances, gut dysfunction, inflammation, and genetics. Through functional testing, personalised nutrition, and targeted supplementation, we create a holistic, evidence-based plan to support emotional well-being and resilience.
  • Can you help if I (or a loved one) have already been diagnosed with a neurodegenerative disease?
    Yes, we work with individuals at all stages of cognitive decline. We use cutting-edge, evidence-based strategies—including the Bredesen ReCode protocol—to optimise brain function.
  • What kind of testing do you offer for brain health concerns?
    We use a combination of functional tests, including blood work, hormone testing, organic acids, gut health assessments, and genetic analysis to identify potential drivers of cognitive issues such as inflammation, nutrient deficiencies, and metabolic imbalances.
  • How does nutrition impact brain health?
    Brain function is heavily influenced by diet, gut health, and nutrient status. We focus on optimising essential nutrients like omega-3s, B vitamins, magnesium, and antioxidants, while also addressing blood sugar balance, gut health, and inflammation.
  • What treatments or strategies do you recommend for brain fog?
    Brain fog is often linked to gut health, nutrient imbalances, hormone imbalance, toxin exposure, or chronic inflammation. We take a personalised approach, identifying and addressing root causes while using targeted dietary, supplement, and lifestylestrategies to restore clarity and focus.
  • Can you help with brain recovery after a head injury or Long COVID symptoms?
    Yes, we support post-concussion recovery and Long COVID-related brain symptoms by reducing neuroinflammation, supporting mitochondrial function, and optimising brain nutrient status. We use personalised nutrition, targeted supplementation, and functional lab testing to help rebuild brain resilience.
  • Do you work with both children and adults with ADHD or autism?
    Yes! We support both children and adults, whether diagnosed or not, using a root-cause approach focused on nutrition, gut health, brain chemistry, and lifestyle strategies.
  • Do I (or my child) need a formal diagnosis to work with you?
    No, a diagnosis is not necessary. We focus on identifying underlying imbalances and supporting brain function with a personalised approach.
  • What kind of testing do you recommend for ADHD and autism?
    We often recommend nutrient panels, hair mineral analysis, organic acids testing, stool analysis, food sensitivity testing, and genetic assessments to uncover nutrient imbalances, gut issues, and brain chemistry factors.
  • Do you offer drug-free support?
    Yes, while we do not replace medical treatment, our approach is holistic and non-medication-based, using nutrition, targeted supplements, and lifestyle interventions to support focus, mood, and behaviour.
  • How long does it take to see improvements?
    Many clients see changes within weeks, but a full programme typically takes 3–6 months, depending on complexity. Long-term benefits come from consistent, personalised interventions.
  • Do you support people with complex and chronic conditions, even if they’ve been told their symptoms are ‘unexplained’?
    Yes! Many of our clients have been through years of medical appointments without clear answers. We specialise in complex, chronic, and poorly understood conditions, including autoimmune diseases, chronic fatigue syndrome (CFS/ME), fibromyalgia, mould illness (CIRS), and other systemic imbalances. Our approach leaves no stone unturned, using advanced testing, personalised nutrition, and targeted interventions to get to the root of your symptoms.
  • How do you approach autoimmune conditions like Hashimoto’s, Rheumatoid Arthritis, or Lupus?
    Autoimmune conditions are multi-factorial, meaning they don’t have a single cause. Our approach identifies and addresses key drivers such as: Gut health & intestinal permeability (leaky gut) Chronic infections or stealth pathogens Nutrient imbalances & inflammation Blood sugar regulation & metabolic health Environmental triggers (mould, toxins, heavy metals, food sensitivities) We create a personalised plan to calm the immune system, reduce inflammation, and support long-term remission where possible.
  • What is Chronic Inflammatory Response Syndrome (CIRS), and how do you test for it?
    CIRS is a multi-system, inflammatory condition triggered by mould, biotoxins, or other environmental exposures. It often leads to symptoms like fatigue, brain fog, joint pain, respiratory issues, and hormone imbalances. We use specialist testing to assess for CIRS, including: Genetic susceptibility (HLA-DR testing) Biotoxin markers (MMP-9, TGF-β1, C4a, VIP, ADH/Osmo tests) Visual Contrast Sensitivity (VCS) testing We then guide you through a step-by-step protocol, including removing exposure, detoxification strategies, immune modulation, and nervous system support to help your body recover.
  • I have Chronic Fatigue Syndrome (CFS/ME) – can you help?
    Yes! CFS/ME is complex and often misunderstood, but we take a functional approach to uncover underlying drivers, including: Mitochondrial dysfunction (poor energy production at the cellular level) Viral reactivation & stealth infections (EBV, Lyme, etc.) Dysautonomia, POTS, and vagus nerve dysfunction Gut imbalances & microbiome dysfunction Hormonal dysregulation (adrenal fatigue, thyroid imbalances) Toxicity (mould, heavy metals, chemicals, or mycotoxins) We personalise a phased recovery plan, working at your body’s pace to restore energy, resilience, and nervous system balance.
  • How does your approach to complex conditions differ from conventional medicine?
    Conventional medicine often focuses on suppressing symptoms with medications, whereas our approach seeks to understand why symptoms are happening in the first place. We take a systems biology perspective, looking at: Nutrient status & deficiencies Metabolic & mitochondrial function Gut health & immune balance Inflammation & nervous system regulation Detoxification pathways Instead of a one-size-fits-all treatment, we create a bespoke roadmap that is tailored to your unique health history, triggers, and biology.
  • I’ve tried everything and still don’t feel better. Can your approach help when nothing else has worked?
    Yes! Many of our clients feel like they have “tried everything” but haven’t had a fully comprehensive, root-cause approach that looks at their genetics, immune function, gut health, toxins, infections, and metabolic function together. We help piece the puzzle together by using cutting-edge testing and a structured plan that goes beyond symptom management—helping you build long-term resilience and recovery.
  • How long does it take to see results?
    This depends on the condition and how long you have been unwell. Some people see improvements within weeks, while deeper healing can take 3–12 months depending on the complexity. We focus on progress, not perfection, working in phases to gradually restore balance and function.
  • Do you offer lab testing to identify what’s driving my condition?
    Yes! We use functional lab testing to gain deeper insights into your unique biochemistry. Depending on your symptoms, we may recommend: Comprehensive blood panels (to assess inflammation, immune function, and nutrient status) Gut microbiome testing (to detect dysbiosis, SIBO, or infections) Mitochondrial & metabolic testing (to assess energy production) Mycotoxin & CIRS testing (for mould-related illness) Hormone & adrenal assessments (including the DUTCH test) Genetic & methylation testing (to identify key biochemical pathways that may need support) Each test is selected based on your history and symptoms, ensuring a targeted and personalised approach.
  • Can you help if I have multiple conditions at once?
    Absolutely. Many of our clients have overlapping conditions, such as: Autoimmune disease + chronic fatigue + gut issues Mould illness + neurological symptoms Long COVID + POTS/dysautonomia + mast cell activation syndrome (MCAS) We specialise in complex, multi-system conditions, helping you to navigate your health journey with clarity and a clear plan.
  • How does gut health impact the brain?
    The gut produces neurotransmitters and inflammatory markers that directly affect brain function. Issues like IBS, SIBO, and leaky gut can cause anxiety, depression, brain fog, and fatigue.
  • What testing do you offer for gut health?
    We use stool analysis, SIBO breath tests, and organic acids testing to assess gut function.
  • How long does gut healing take?
    Most clients see significant improvements within 3–6 months with a structured, root-cause approach.
  • How do hormones impact brain function?
    Hormonal shifts can lead to brain fog, mood swings, anxiety, poor memory, and sleep issues. We assess and support oestrogen, progesterone, cortisol, thyroid function, and blood sugar balance to restore cognitive clarity.
  • What tests do you offer for hormone-related brain symptoms?
    We use DUTCH hormone testing, thyroid panels, blood sugar markers, and micronutrient assessments to identify hormonal imbalances and nutrient deficiencies.
  • Can you help with perimenopause and menopause symptoms?
    Yes! We support cognitive function, mood stability, sleep, and energy levels using personalised nutrition, supplements, and hormone-balancing strategies.
  • Do you offer natural alternatives to HRT?
    We provide both HRT-supportive and natural approaches, depending on your preferences. We focus on phytoestrogens, adrenal support, and targeted nutrients to balance hormones naturally. We also work closely alongside a prescribing doctor who is able to personalise and prescribe body identical HRT as required.
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